Divergent Signal Transduction Responses to Infection with Attaching and Effacing Escherichia coli

Experimental infection of young chicks with attaching and effacing Escherichia coli.

Young chicks were inoculated with six different strains of attaching and effacing Escherichia coli isolated from the feces of calves, pigs, chicks, and humans. Colibacilli of some serotypes had colonized the cecum of chicks by 7 days after inoculation. The characteristic lesions associated with bacterial attachment were also seen on the mucosal surface of the cecum. Electron microscopy revealed...

Natural and Experimental Infection with an Attaching and Effacing Strain of Escherichia coli in Calvest

Natural and experimental infection with an attaching and effacing strain of Escherichia coli in calves.

Gnotobiotic calves were inoculated with an O5:K4:H-, urease-positive strain of Escherichia coli isolated from a 2-day-old calf with diarrhea. The calves developed elevated temperatures and passed loose mucoid feces, with or without blood. The E. coli strain was negative for heat-stable and heat-labile enterotoxins but produced high levels of Shiga-like toxin. Bacteria attached diffusely to the ...

Cytoskeletal composition of attaching and effacing lesions associated with enteropathogenic Escherichia coli adherence to HeLa cells.

The cytoskeletal lesions associated with enteropathogenic Escherichia coli adhering to cultured HeLa epithelial cells were examined by immunofluorescence microscopy. The microfilament-associated proteins actin, alpha-actinin, talin, and ezrin were localized with adherent enteropathogenic E. coli, whereas tropomyosin, keratin and vimentin (intermediate filaments), tubulin (microtubules), and vin...

Attaching and effacing lesions in the intestines of an adult goat associated with natural infection with Escherichia coli O145.

THERE have been few reports of attaching and effacing Escherichia coli (AEEC) infections in goats. A severe outbreak was recorded by Drolet and others (1994) affecting neonatal goat kids, of which 21 of 34 born alive died after having diarrhoea. A further case (Duhamel and others 1992) involved a goat approximately two months old, with severe diarrhoea of three weeks’ duration. This animal was ...